For US residents only.

How Treatment May Help

VOTRIENT® (pazopanib) tablets

Before you start taking VOTRIENT

Before you start taking VOTRIENT, your health care provider needs to know about the information listed below. He or she may provide specific advice to help you get the most from your treatment with VOTRIENT.

Before you take VOTRIENT, tell your health care provider if you:

  • Have or had liver problems. You may need a lower dose of VOTRIENT or your health care provider may prescribe a different medicine to treat your advanced soft tissue sarcoma
  • Have high blood pressure
  • Have heart problems or an irregular heartbeat, including QT prolongation
  • Have a history of stroke
  • Have headaches, seizures, or vision problems
  • Have coughed up blood in the last 6 months
  • Had bleeding of your stomach or intestines in the last 6 months
  • Have a history of a tear (perforation) in your stomach or intestine, or an abnormal connection between 2 parts of your gastrointestinal tract (fistula)
  • Have had blood clots in a vein or in the lung
  • Have thyroid problems
  • Had recent surgery (within the last 7 days) or are going to have surgery
  • Have any other medical conditions
  • Are pregnant or plan to become pregnant. VOTRIENT can harm your unborn baby. You should not become pregnant while you are taking VOTRIENT
  • Are using birth control. You should use effective birth control during treatment with VOTRIENT and for 2 weeks after your last dose
  • Are breastfeeding or plan to breastfeed. It is not known if VOTRIENT passes into your breast milk. You and your health care provider should decide if you will take VOTRIENT or breastfeed. You should not do both